Fragmenta de viribus medicamentorum positivis sive in sano corpore humano observatis (“Fragmentary Observations Relative to the Positive Powers of Medicines on the Human Body”) was published in the year 1805, written in Latin language. It was published in Leipzig by M/s Sumpter Joan Ambrose Barth.
This work, containing the first collection of remedies which had been proven on a healthy subject, deals with the remedies together with a number of symptoms found by proving.
Thus, Hahnemann obtained, in the years 1796-1798 a partly usable materia medica, with the help of which he began to treat his patients according to his newly discovered therapeutic principle. But he soon noticed that the extant reports of others were inadequate, inaccurate and consequently thoroughly unreliable. He therefore arrived at a further determination — namely, to observe the effect of medicines on himself. Hahnemann says “I made it a serious occupation for myself to prove several drugs on the healthy human body.” The results of these investigations were then collected in his book.
It has two volumes.
1- Pars Prima- The first volume was published in 1805. It has 8 pages of introduction and 269 pages of main text of the book. The first and smaller part of the book contains the symptoms of all the remedies which Hahnemann had proved on himself, in so far as they are not taken from other toxicological observations.
2- Pars Secunda- The second volume was the Repertory or Index. It has 6 pages of Preface and a Repertory of 470 pages.
This book contains 27 drugs which were as follows:
– Aconitum napellus.
– Acris tinctura (Causticum).
– Arnica montana.
– Capsicum annuum.
– Copaifera balsamum.
– Cuprum vitriolatum.
– Melanpodium helleborus.
– Nux vomica.
– Papaver somniferum (Opium).
– Veratrum album.
Out of the 27 drugs, 24 drugs are from vegetable kingdom, 1 from animal kingdom and 2 are from mineral kingdom. The maximum symptoms were recorded in Pulsatilla (280) and minimum in Copaifera balsamum (17). Out of the 27 drugs, 22 were incorporated into Reine Arzneimittellehre ( i.e. Materia medica pura). Of the remaining 5, Cuprum and Mezerium appeared later in the second edition of Die Chronischen Krankheiten Vol. 3 (1837) and Vol. 4 (1838) respectively, whilst Cantharis, Copaiva, and Valeriana were not furthered by Hahnemann.
He also mentioned this, in his book Organon of medicine, § 109 footnote 3, – ‘The first fruits of these labours, as perfect as they could be at that time, I recorded in the Fragmenta de viribus medicamentorum positivis, sive in sano corpore humano observatis, pts. i, ii, Lipsiae, 8, 1805 ap. J. A. Barth.’
German and French translations of the book were also published. Fragments sur les effets positives des medicaments observes chez l’homme sin, Pars Prima was translated by Champaeux and Milcent in French in 1855 and it was published at Brussels. This translation was reprinted in 1958. Marion Wetterman translated this into German in 2000, as “Fragmenta de viribus medicamentorum”– the first homoeopathic materia medica, Faculty of Medicine, Eberhand-Karls- University, Tubingen.
In 1834 Dr. F.F Quinn, father of British Homoeopathy, edited this book and published it in one volume from London.